Background/Objectives: As with many viral fusion proteins, the native conformation of SARS-CoV-2 Spike is metastable.Most COVID-19 vaccines utilize a stabilized Spike (Spike-2P) containing two proline substitutions, and subsequently, a further stabilized variant with four additional proline substitutions, Spike-6P, has been developed.In an alternat
Abstract Prostate cancer (PCa) is a highly common type of malignancy and affects millions of men in the world since it is easy to recur or emerge therapy resistance.Therefore, it is urgent to find 7gm pravana novel treatments for PCa patients.In the current study, we found that tegaserod maleate (TM), an FDA-approved agent, inhibited proliferation,
Health tourism is one of the effective factors in the economic prosperity of the countries, the beautiful nature and hot springs of Ardebil province makes it a good destination for health tourism.The aim of this study was to investigate demographic and socioeconomic characteristics of health tourists of Ardebil.To investigate the viewpoint of healt
This article examines the impact of socially constructed meanings regarding social minorities on the development of inclusion policies for these groups in higher education.This analysis is based on a comparative case study between Global South and Global North, specifically focusing on a dialogue between Brazil and Nordic contexts.Social minorities
The present work focuses on the long-term coastal monitoring of the Atlantic surface inflow into the Mediterranean basin through the Strait of Gibraltar.Hourly current maps provided during 2016–2017 by a High Frequency radar (HFR) system were used to characterize the Atlantic Jet (AJ) since changes in its speed and direction modulate the uppe